Senior Supervisor – Downstream Biomanufacturing

Location: Madison, WI

Pay: up to 53/hr
Schedule: Sunday–Wednesday, 10:00 PM–8:00 AM (Overnight Shift)
Employment Type: Contract, guaranteed through March 13, 2027, with potential for extension and permanent offer based on business needs

About the Opportunity

Adecco is assisting a leading biopharmaceutical organization in seeking an experienced Senior Supervisor, Downstream Biomanufacturing to oversee overnight manufacturing operations and lead a team responsible for producing biologics drug substance in a regulated clinical and commercial manufacturing environment.

This is a hands-on leadership role that combines direct manufacturing floor support with employee development, production oversight, and operational execution. The Senior Supervisor will guide a team of approximately 5–15 employees, ensuring manufacturing activities are completed safely, efficiently, and in accordance with established cGMP requirements.

The ideal candidate brings a strong understanding of downstream biologics manufacturing, proven leadership experience, and the ability to foster a culture of quality, accountability, and continuous improvement.

Key Responsibilities

• Lead and oversee overnight downstream manufacturing operations, providing hands-on floor support and direction to a team of approximately 5–15 employees.

• Ensure successful execution of biologics manufacturing activities, including column chromatography, normal flow filtration (NFF), tangential flow filtration (TFF), viral reduction/filtration, and bulk drug substance filling.

• Maintain compliance with cGMP requirements, company SOPs, specifications, and applicable regulatory guidelines.

• Ensure manufacturing readiness, production schedule adherence, and timely completion of batch activities.

• Provide coaching, technical guidance, and employee development to promote consistent execution and a right-first-time quality culture.

• Coordinate activities with supervisors across other shifts to maintain operational consistency and standard work practices.

• Support customer and Person in Plant (PIP) activities, addressing operational questions and ensuring alignment with program requirements.

• Drive continuous improvement initiatives, process optimization, and effective use of personnel and resources.

• Participate in recruiting, hiring recommendations, performance evaluations, employee development, and application of company policies.

• Collaborate with Quality Assurance and other site functions to support manufacturing objectives, compliance, and overall site performance.

Qualifications

Candidates should meet one of the following education and experience combinations:

• Doctorate in a scientific, engineering, or biomanufacturing discipline with at least 3 years of relevant experience.

• Master's degree in a related discipline with at least 6 years of relevant experience.

• Bachelor's degree in a related discipline with at least 7 years of relevant experience.

• Associate degree in a related discipline with at least 9 years of relevant experience.

• High school diploma with at least 10 years of relevant experience.

Additional Requirements:

• More than 2 years of leadership or supervisory experience.

• Background in biologics or pharmaceutical manufacturing, preferably within downstream processing.

• Understanding of cGMP requirements, data integrity, SOP compliance, and applicable FDA, EMA, and ICH guidelines.

• Strong communication and interpersonal skills, including the ability to lead challenging discussions and communicate technical information to diverse audiences.

• Ability to manage competing priorities, coordinate multiple manufacturing activities, and make sound operational decisions.

• Experience in cleanroom environments, aseptic techniques, and/or general laboratory equipment is preferred.

• Previous cGMP manufacturing experience is preferred.

Schedule & Assignment Details

• Shift: Sunday–Wednesday, 10:00 PM–8:00 AM.

• Location: Madison, WI.

• Assignment: Guaranteed through March 13, 2027.

• Extension: Potential for additional time based on business needs.

Why Work with Adecco?

Adecco offers access to opportunities with leading employers, along with support throughout the hiring and assignment process.

Depending on eligibility, benefits may include:

• Medical, dental, and vision insurance.

• 401(k) retirement savings plan.

• Weekly pay.

• Access to employee discounts and additional resources.

How to Apply

If you have a background in downstream biologics manufacturing and experience leading teams in a regulated production environment, we'd love to hear from you. Apply today to be considered for this opportunity!

Adecco is an Equal Opportunity Employer.

Pay Details: $50.00 to $53.00 per hour

Benefit offerings available for our associates include medical, dental, vision, life insurance, short-term disability, additional voluntary benefits, EAP program, commuter benefits and a 401K plan. Our benefit offerings provide employees the flexibility to choose the type of coverage that meets their individual needs. In addition, our associates may be eligible for paid leave including Paid Sick Leave or any other paid leave required by Federal, State, or local law, as well as Holiday pay where applicable.

Equal Opportunity Employer/Veterans/Disabled

Military connected talent encouraged to apply

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The Company will consider qualified applicants with arrest and conviction records in accordance with federal, state, and local laws and/or security clearance requirements, including, as applicable:

• The California Fair Chance Act
• Los Angeles City Fair Chance Ordinance
• Los Angeles County Fair Chance Ordinance for Employers
• San Francisco Fair Chance Ordinance

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